Description

5-Amino-2,3-Dihydro-1H-Indene-1-Carboxylic Acid Methyl Ester is a high-purity, functionalized indane derivative serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in providing a rigid, fused-ring scaffold with both amino and ester functionalities, enabling the construction of complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and metabolic conditions.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce the indane core with defined stereochemistry into more complex molecules.
• Agrochemical Research: Intermediate for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Starting material for synthesizing specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Biology: Used in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: Serves as a versatile substrate for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	5-Amino-2,3-Dihydro-1H-Indene-1-Carboxylic Acid Methyl Ester
CAS No.	754153-28-1
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	Methyl 5-amino-2,3-dihydro-1H-indene-1-carboxylate; 1H-Indene-1-carboxylic acid, 5-amino-2,3-dihydro-, methyl ester; 5-Aminoindane-1-carboxylic acid methyl ester; 5-Amino-1-indancarboxylic acid methyl ester; Methyl 5-aminoindane-1-carboxylate; 754153-28-1; 5-Amino-2,3-dihydro-1H-indene-1-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Amino-2,3-Dihydro-1H-Indene-1-Carboxylic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory support documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.