Description

3-(3,4-Dichlorophenyl)-3-Pyrrolidinol is a high-value pyrrolidine-based chiral building block and pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of potential drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the dichlorophenyl moiety is critical for activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals.
• Academic and R&D: Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	3-(3,4-Dichlorophenyl)-3-Pyrrolidinol
CAS No.	754133-38-5
Molecular Formula	C10H11Cl2NO
Molecular Weight	232.11 g/mol
Synonyms	3-(3,4-Dichlorophenyl)pyrrolidin-3-ol; 3-Pyrrolidinol, 3-(3,4-dichlorophenyl)-; 3-Hydroxy-3-(3,4-dichlorophenyl)pyrrolidine; (3R)-3-(3,4-Dichlorophenyl)-3-pyrrolidinol (for enantiomer); (3S)-3-(3,4-Dichlorophenyl)-3-pyrrolidinol (for enantiomer); 3-(3,4-DCP)Pyrrolidinol
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dichlorophenyl)-3-Pyrrolidinol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specific enantiomer) or Contact
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.