Description

1,1'-Spirobi[1H-Indene]-6,6'-Diol, 5,5'-Diamino-2,2',3,3'-Tetrahydro-3,3,3',3'-Tetramethyl- is a high-purity, multifunctional chiral diamine-diol compound with a unique spirocyclic structure. This compound matters as a sophisticated building block and ligand precursor for advanced material synthesis, offering precise stereochemical control. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalysis Ligand: Used as a precursor for developing proprietary chiral ligands and catalysts for enantioselective synthesis.
• Advanced Polymer Monomer: Employed in the production of high-performance, specialty polyimides, polyamides, and epoxy resins with enhanced thermal and mechanical properties.
• Agrochemical Synthesis: Acts as a critical intermediate for creating novel, optically active pesticides and herbicides.
• Material Science Research: Utilized in R&D for organic electronic materials, such as hole-transport layers or non-linear optical (NLO) materials.
• Coordination Chemistry: Functions as a chelating agent for metal complexes used in sensing, imaging, or catalysis applications.

Basic Information

Product Name	1,1'-Spirobi[1H-Indene]-6,6'-Diol, 5,5'-Diamino-2,2',3,3'-Tetrahydro-3,3,3',3'-Tetramethyl-
CAS No.	753437-92-2
Molecular Formula	C25H30N2O2
Molecular Weight	390.52 g/mol
Synonyms	5,5'-Diamino-3,3,3',3'-tetramethyl-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-6,6'-diol; 1,1'-Spirobiindane-6,6'-diol, 5,5'-diamino-3,3,3',3'-tetramethyl-; (R)-5,5'-Diamino-3,3,3',3'-tetramethyl-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-6,6'-diol; (S)-5,5'-Diamino-3,3,3',3'-tetramethyl-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-6,6'-diol; Spirobiindane Diamine Diol; TADDOL Diamine Derivative; Chiral Spiro Diol-Diamine
EINECS	Contact for details

Quality Control

Our 1,1'-Spirobi[1H-Indene]-6,6'-Diol, 5,5'-Diamino-2,2',3,3'-Tetrahydro-3,3,3',3'-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and chiral purity analysis to ensure compliance with customer specifications and cGMP guidelines where required. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiomerically pure grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.