Description

1,4-Cyclohexanediol, 2,6-Diamino-, (1Alpha,2Alpha,4Alpha,6Alpha)- (9Ci) is a high-purity, stereochemically defined diamine-diol compound that serves as a versatile chiral building block for advanced organic synthesis. Its unique structure, featuring both amino and hydroxyl functional groups in a rigid cyclohexane framework, makes it a critical intermediate for creating complex molecules with precise spatial orientation. This compound is essential for research and development in the pharmaceutical and fine chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst & Ligand Synthesis: Used to construct sophisticated chiral ligands and organocatalysts for enantioselective synthesis, improving yield and purity in fine chemical production.
• Advanced Polymer Chemistry: Serves as a monomer or cross-linking agent for producing high-performance, specialty polymers with tailored thermal and mechanical properties.
• Agrochemical Research: Employed in the development of new, more effective chiral herbicides and pesticides with improved environmental profiles.
• Material Science: Investigated for use in advanced materials such as liquid crystals, epoxy resin hardeners, and corrosion inhibitors.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry research and process development in discovery laboratories.

Basic Information

Product Name	1,4-Cyclohexanediol, 2,6-Diamino-, (1Alpha,2Alpha,4Alpha,6Alpha)- (9Ci)
CAS No.	752928-86-2
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	(1α,2α,4α,6α)-2,6-Diaminocyclohexane-1,4-diol; (1R,2R,4R,6R)-2,6-Diaminocyclohexane-1,4-diol; cis,cis-2,6-Diamino-1,4-cyclohexanediol; 2,6-Diamino-1,4-cyclohexanediol (stereoisomer); 1,4-Cyclohexanediol, 2,6-diamino-, (1R,2R,4R,6R)-; 752928-86-2; Chiral Diamine-Diol Building Block
EINECS	Contact for details

Quality Control

Our 1,4-Cyclohexanediol, 2,6-Diamino-, (1Alpha,2Alpha,4Alpha,6Alpha)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, strength, and compositional integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment ensures material consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.