Description

Ethanone, 1-(1-Azabicyclo[2.2.1]Hept-3-Yl)-2-Bromo-, Exo- (9Ci) is a specialized brominated ketone derivative featuring a rigid norbornane-like azabicyclic scaffold. This compound is a high-value chemical intermediate prized for its unique three-dimensional structure, which is critical for imparting specific stereochemical and pharmacological properties in advanced syntheses. It is primarily utilized by pharmaceutical R&D and fine chemical sectors for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its bicyclic structure for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in synthesizing specialty polymers and advanced organic materials with specific structural properties.

Basic Information

Product Name	Ethanone, 1-(1-Azabicyclo[2.2.1]Hept-3-Yl)-2-Bromo-, Exo- (9Ci)
CAS No.	752169-32-7
Molecular Formula	C8H12BrNO
Molecular Weight	218.09 g/mol
Synonyms	2-Bromo-1-(exo-3-nortropanyl)ethanone; 1-(1-Azabicyclo[2.2.1]hept-3-yl)-2-bromoethanone (exo-); exo-2-Bromo-1-(3-nortropanyl)ethanone; exo-3-(2-Bromoacetyl)nortropane; Bromoacetyl nortropane (exo isomer); Nortropane-3-yl bromomethyl ketone (exo); 752169-32-7; Bromo ketone nortropane derivative
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. Production is aligned with cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.