Description

1H-Indole-4,7-Diol, Octahydro-2-(Hydroxymethyl)-2-Mercapto-, (2R,3As,4S,7S,7As)- (9Ci) is a complex, stereochemically defined indole derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring multiple functional groups including diol, hydroxymethyl, and mercapto moieties, makes it a versatile precursor for constructing pharmacologically active molecules. This high-value intermediate is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder research.
• Advanced Organic Synthesis: Used as a complex building block for constructing natural product analogs and other structurally intricate organic molecules in medicinal chemistry.
• Biochemical Research: Serves as a precursor or standard in studies involving enzyme inhibition, receptor binding, or other biochemical pathways where its specific stereochemistry is relevant.
• Asymmetric Catalysis Ligand Precursor: Potential use in the synthesis of novel chiral ligands or organocatalysts due to its multiple stereocenters and functional groups.

Basic Information

Product Name	1H-Indole-4,7-Diol, Octahydro-2-(Hydroxymethyl)-2-Mercapto-, (2R,3As,4S,7S,7As)- (9Ci)
CAS No.	750646-58-3
Molecular Formula	C9H17NO3S
Molecular Weight	219.30 g/mol
Synonyms	(2R,3aS,4S,7S,7aS)-Octahydro-2-(hydroxymethyl)-2-mercapto-1H-indole-4,7-diol; (2R,3aS,4S,7S,7aS)-2-(Hydroxymethyl)-2-mercaptooctahydro-1H-indole-4,7-diol; 1H-Indole-4,7-diol, octahydro-2-(hydroxymethyl)-2-mercapto-, (2R,3aS,4S,7S,7aS)-; Octahydro-2-(hydroxymethyl)-2-mercapto-1H-indole-4,7-diol (stereoisomer).
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We employ advanced analytical techniques including HPLC, chiral analysis, and NMR spectroscopy to verify the stereochemical integrity and chemical purity critical for its intended synthetic uses.

Storage

Preserve in a tightly closed container, protected from light. Due to its property of being easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.