Description

2-(4-Chloro-Phenylsulfanyl)-Quinoline-3-Carbaldehyde is a versatile and high-value organic building block characterized by its quinoline core functionalized with a chlorophenylsulfanyl group and an aldehyde. This compound matters for its role as a key synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs), enabling complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysis, and functional dyes due to its electron-rich quinoline system.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex fused-ring systems and as a substrate for further functionalization (e.g., via the reactive aldehyde group).
• Ligand Preparation: Useful for the synthesis of specialized ligands used in transition metal catalysis and coordination chemistry.

Basic Information

Product Name	2-(4-Chloro-Phenylsulfanyl)-Quinoline-3-Carbaldehyde
CAS No.	749920-53-4
Molecular Formula	C₁₆H₁₀ClNOS
Molecular Weight	299.77 g/mol
Synonyms	2-[(4-Chlorophenyl)thio]quinoline-3-carboxaldehyde; 2-(4-Chlorophenylsulfanyl)quinoline-3-carbaldehyde; 3-Formyl-2-(4-chlorophenylthio)quinoline; Quinoline-3-carbaldehyde, 2-[(4-chlorophenyl)thio]-; 749920-53-4; 2-(p-Chlorophenylthio)quinoline-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-Phenylsulfanyl)-Quinoline-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and light-sensitive, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to air and light during use.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.