Description

1-(4-Bromo-3-Fluorophenyl)Cyclopropane-1-Carboxylic Acid is a high-value, multi-functional organic building block characterized by its unique cyclopropane-carboxylic acid core substituted with bromo and fluoro groups on the aromatic ring. This compound is essential for advanced organic synthesis, where its reactive handles enable precise molecular construction. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Serves as a crucial precursor for developing advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated cyclopropane moiety.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis, benefiting from the steric and electronic properties of the cyclopropane ring.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials where fluorinated aromatic units enhance stability and performance.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Used in exploratory chemistry within university laboratories and corporate R&D centers for method development and novel compound library generation.

Basic Information

Product Name	1-(4-Bromo-3-Fluorophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	749269-74-7
Molecular Formula	C10H8BrFO2
Molecular Weight	259.07 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)cyclopropanecarboxylic acid; 1-(4-Bromo-3-fluorophenyl)cyclopropanecarboxylate; Cyclopropanecarboxylic acid, 1-(4-bromo-3-fluorophenyl)-; 4-Bromo-3-fluoro-α,α-cyclopropanebenzenecarboxylic acid; 749269-74-7; 1-(4-Bromo-3-fluoro-phenyl)-cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromo-3-Fluorophenyl)Cyclopropane-1-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP (current Good Manufacturing Practice) principles and compliance with REACH regulations ensures a reliable supply for global research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.