Description

Benzeneacetic Acid, α-Amino-2-Hydroxy-5-Methoxy- (9Ci) is a specialized aromatic amino acid derivative with a distinct substitution pattern that imparts unique chemical reactivity and biological activity. This compound serves as a critical high-purity building block in advanced organic synthesis, particularly for the development of novel pharmaceutical candidates and fine chemicals. It is primarily required by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its multifunctional (amino, hydroxy, methoxy) aromatic scaffold.
• Peptidomimetic Synthesis: Serves as a non-natural amino acid analog for constructing modified peptides with enhanced stability or biological properties.
• Ligand and Catalyst Development: Employed in the synthesis of specialized chelating ligands or organocatalysts for asymmetric synthesis.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Bioconjugation Chemistry: The reactive functional groups enable its use in linker chemistry for antibody-drug conjugates (ADCs) or other bioconjugates.

Basic Information

Product Name	Benzeneacetic Acid, α-Amino-2-Hydroxy-5-Methoxy- (9Ci)
CAS No.	749188-07-6
Molecular Formula	C10H13NO4
Molecular Weight	211.22 g/mol
Synonyms	2-Amino-2-(2-hydroxy-5-methoxyphenyl)acetic acid; 5-Methoxy-2-hydroxyphenylglycine; α-Amino-(2-hydroxy-5-methoxyphenyl)acetic acid; (2-Hydroxy-5-methoxyphenyl)glycine; L-748,188 (related compound identifier); Aromatic amino acid derivative; 2-Hydroxy-5-methoxy-DL-phenylglycine; Research compound 749188-07-6
EINECS	Contact for details

Quality Control

Every batch of our Benzeneacetic Acid, α-Amino-2-Hydroxy-5-Methoxy- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support research and development applications, with purity typically meeting or exceeding 97% (HPLC). A detailed Certificate of Analysis (COA) containing results for identity, assay, purity, and related substances is supplied with each shipment to ensure full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.