Description

Benzene, 1-Methoxy-4-[(1S)-1-Methyl-2-Nitroethyl]- (9Ci) CAS NO 748183-59-7 is a chiral, nitro-substituted aromatic compound of significant interest in advanced organic synthesis. Its value lies in its role as a versatile chiral building block and intermediate for the development of complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in fine chemical, agrochemical, and pharmaceutical R&D who require high-purity, structurally defined intermediates for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and cardiovascular diseases.
• Agrochemical Research: Used in the development of novel, optically active herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical purity.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymeric materials with specific optical properties.

Basic Information

Product Name	Benzene, 1-Methoxy-4-[(1S)-1-Methyl-2-Nitroethyl]- (9Ci)
CAS No.	748183-59-7
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	1-Methoxy-4-[(1S)-1-methyl-2-nitroethyl]benzene; (S)-1-Methoxy-4-(1-methyl-2-nitroethyl)benzene; p-Methoxy-β-methyl-β-nitrostyrene (reduction product precursor); (S)-4-Methoxy-α-methyl-β-nitrophenethyl; Benzene, 1-methoxy-4-[(1S)-1-methyl-2-nitroethyl]- (9CI); Aromatic nitro compound intermediate
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-Methoxy-4-[(1S)-1-Methyl-2-Nitroethyl]- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. We operate under a cGMP-compliant quality management system, ensuring traceability and documentation suitable for regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.