Description

Benzoic Acid, 2-Amino-5-(Trifluoromethoxy)-, Hydrochloride is a high-value, halogenated aromatic amine hydrochloride salt, distinguished by its trifluoromethoxy substituent which imparts unique electronic and steric properties. This compound is a critical pharmaceutical intermediate and research chemical used in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for medicinal chemistry research and fine chemical manufacturing, particularly for companies developing novel therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the stability of the trifluoromethoxy group.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals due to its aromatic and halogenated structure.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in R&D laboratories.
• Biochemical Research: Utilized in proteomics and enzyme inhibition studies as a specialized molecular probe.

Basic Information

Product Name	Benzoic Acid, 2-Amino-5-(Trifluoromethoxy)-, Hydrochloride
CAS No.	746671-63-6
Molecular Formula	C8H7F3NO3•HCl
Molecular Weight	273.60 g/mol
Synonyms	2-Amino-5-(trifluoromethoxy)benzoic acid hydrochloride; 5-(Trifluoromethoxy)anthranilic acid hydrochloride; 2-Amino-α,α,α-trifluoro-p-anisic acid hydrochloride; 2-Amino-5-(trifluoromethoxy)benzoic acid HCl; 5-(Trifluoromethoxy)-2-aminobenzoic acid hydrochloride; Anthranilic acid, 5-(trifluoromethoxy)-, hydrochloride; 2-Carboxy-4-(trifluoromethoxy)aniline hydrochloride
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 2-Amino-5-(Trifluoromethoxy)-, Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.