Description

4-Quinazolinamine, 6-[3-(2-Pyridinyl)-1H-Pyrazol-4-Yl]- is a high-purity heterocyclic organic compound featuring a quinazolinamine core linked to a pyrazolylpyridine moiety. This complex molecular architecture makes it a valuable pharmacological intermediate and key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly kinase inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small-molecule drugs, especially for oncology research.
• Kinase Inhibitor Development: Used as a core scaffold or building block in the design and discovery of novel protein kinase inhibitors.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Biochemical Tool Compound: Acts as a reference standard or probe in biochemical and cellular assays to study specific biological pathways.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to construct more complex, biologically active molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-Quinazolinamine, 6-[3-(2-Pyridinyl)-1H-Pyrazol-4-Yl]-
CAS No.	746667-28-7
Molecular Formula	C16H12N6
Molecular Weight	288.31 g/mol
Synonyms	6-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)quinazolin-4-amine; 6-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-4-quinazolinamine; 4-Amino-6-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)quinazoline; CAS 746667-28-7; 6-(3-(2-Pyridyl)-1H-pyrazol-4-yl)-4-quinazolinamine; Pyrazolylpyridine-substituted quinazolinamine
EINECS	Contact for details

Quality Control

Our 4-Quinazolinamine, 6-[3-(2-Pyridinyl)-1H-Pyrazol-4-Yl]- is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.