Description

8-Bromo-6-Fluoro-3,4-Dihydro-2H-1-Benzopyran is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated benzopyran core structure. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable bromo and fluoro substituents.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection products.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	8-Bromo-6-Fluoro-3,4-Dihydro-2H-1-Benzopyran
CAS No.	746638-33-5
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	8-Bromo-6-fluoro-3,4-dihydro-2H-chromene; 8-Bromo-6-fluoro-2H-chromene; 6-Fluoro-8-bromo-3,4-dihydro-2H-1-benzopyran; 8-Bromo-6-fluoro-3,4-dihydro-2H-chromene; 746638-33-5; 8-Bromo-6-fluoro-2H-1-benzopyran; 8-Bromo-6-fluoro-3,4-dihydro-2H-1-chromene
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Fluoro-3,4-Dihydro-2H-1-Benzopyran is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.