Description

4-Chloroquinoline-3-Boronic Acid, 97% is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters for its critical role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for anti-malarial and anti-cancer research.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for creating carbon-carbon bonds with aryl/heteroaryl halides.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with quinoline scaffolds.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for catalysts or components for OLEDs.
• Chemical Biology Probes: Utilized to build tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical suppliers offering bespoke synthesis services.

Basic Information

Product Name	4-Chloroquinoline-3-Boronic Acid, 97%
CAS No.	745784-09-2
Molecular Formula	C9H7BClNO2
Molecular Weight	207.42 g/mol
Synonyms	(4-Chloroquinolin-3-yl)boronic acid; 3-Borono-4-chloroquinoline; 4-Chloro-3-quinolineboronic acid; 4-Chloro-quinoline-3-boronic acid; Quinoline, 4-chloro-3-borono-; 745784-09-2; B-(4-Chloro-3-quinolyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloroquinoline-3-Boronic Acid, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with documented specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.