Description

3-(Pyridin-2-Ylsulfanylmethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique piperidine-pyridine-thioether scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used in structure-activity relationship (SAR) studies and lead optimization due to its piperidine and pyridine motifs.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides.
• Ligand Synthesis: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the creation of tool compounds for studying biological pathways and protein function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	3-(Pyridin-2-Ylsulfanylmethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	745066-48-2
Molecular Formula	C16H24N2O2S
Molecular Weight	308.44 g/mol
Synonyms	1-Boc-3-[(pyridin-2-ylthio)methyl]piperidine; tert-Butyl 3-[(pyridin-2-ylsulfanyl)methyl]piperidine-1-carboxylate; 3-[(Pyridin-2-ylthio)methyl]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-[(2-pyridylthio)methyl]piperidine; 3-(2-Pyridylthiomethyl)piperidine-1-carboxylic acid tert-butyl ester; 745066-48-2; Boc-3-(Pyridin-2-ylthiomethyl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(Pyridin-2-Ylsulfanylmethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.