Description

Triphenyl[(Tetrahydro-2H-Pyran-4-Yl)Methyl]Phosphonium Iodide is a specialized organophosphonium salt that serves as a versatile reagent in advanced organic synthesis. Its value lies in its role as a key precursor for generating stabilized ylides, enabling critical carbon-carbon bond-forming reactions essential for constructing complex molecular architectures. This high-purity intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Wittig Reaction Reagent: As a precursor to a stabilized ylide for the stereoselective synthesis of alkenes containing the tetrahydro-2H-pyran-4-yl moiety.
• Pharmaceutical Intermediate: In the research and development of complex drug molecules, particularly those requiring specific heterocyclic frameworks.
• Ligand Synthesis: For the preparation of specialized phosphine ligands used in catalysis.
• Material Science Research: As a building block for novel ionic liquids or functional organic materials.
• Academic & Process Chemistry: A valuable tool for methodological development and scale-up studies in synthetic organic chemistry.

Basic Information

Item	Detail
Product Name	Triphenyl[(Tetrahydro-2H-Pyran-4-Yl)Methyl]Phosphonium Iodide
CAS No.	745052-92-0
Molecular Formula	C24H26IO1P
Molecular Weight	488.34 g/mol
Synonyms	4-(Triphenylphosphoniomethyl)tetrahydropyran Iodide; (Tetrahydro-2H-pyran-4-ylmethyl)triphenylphosphonium Iodide; Triphenyl(4-tetrahydropyranylmethyl)phosphonium Iodide; (Tetrahydro-2H-pyran-4-yl)methyltriphenylphosphonium Iodide; THP-Methyltriphenylphosphonium Iodide; CAS 745052-92-0
EINECS	Contact for details

Quality Control

Our Triphenyl[(Tetrahydro-2H-Pyran-4-Yl)Methyl]Phosphonium Iodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.