Description

5-Amino-2-Bromo-4-Methylbenzoic Acid is a high-purity, multi-functional benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and bromo substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, where the bromine atom offers a handle for further functionalization to optimize biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Dye and Pigment Manufacturing: Functions as an intermediate in the production of advanced organic dyes and pigments, contributing to color fastness and stability.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom chemical synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	5-Amino-2-Bromo-4-Methylbenzoic Acid
CAS No.	745048-63-9
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Bromo-5-amino-4-methylbenzoic acid; 4-Methyl-5-amino-2-bromobenzoic acid; Benzoic acid, 5-amino-2-bromo-4-methyl-; 5-Amino-2-bromo-p-toluic acid; 2-Bromo-4-methyl-5-aminobenzoic acid; 5-Amino-2-bromo-4-methylbenzoic acid (primary IUPAC)
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-2-Bromo-4-Methylbenzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets rigorous in-house specifications. A detailed Certificate of Analysis (COA) with batch-specific results from techniques including HPLC, NMR, and IR is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.