Description

1,2-Cyclohexanediol, 3,5-Diamino-, [1R-(1Alpha,2Alpha,3Beta,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral diamine-diol building block of significant interest in advanced organic synthesis. Its unique bifunctional structure, featuring both amino and hydroxyl groups on a rigid cyclohexane backbone, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies in the development of chiral ligands, catalysts, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in areas requiring high stereochemical purity.
• Asymmetric Catalyst & Ligand Synthesis: Serves as a core structure for developing novel chiral catalysts and ligands used in enantioselective transformations.
• Advanced Material Research: Used in the development of specialty polymers, dendrimers, and functional materials where precise molecular geometry is critical.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and tools for studying biological systems.
• Fine Chemical Synthesis: Acts as a building block for complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	1,2-Cyclohexanediol, 3,5-Diamino-, [1R-(1Alpha,2Alpha,3Beta,5Alpha)]- (9Ci)
CAS No.	744980-63-0
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	(1R,2R,3S,5R)-3,5-Diaminocyclohexane-1,2-diol; (1R,2R,3S,5R)-3,5-Diamino-1,2-cyclohexanediol; 3,5-Diamino-1,2-cyclohexanediol (stereoisomer); cis-3,5-Diaminocyclohexane-1,2-diol; Chiral Cyclohexane Diamine Diol; CAS 744980-63-0
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclohexanediol, 3,5-Diamino-, [1R-(1Alpha,2Alpha,3Beta,5Alpha)]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.