Description

2-Chloro-7-Iodoquinazolin-4(3H)-One is a high-purity, halogenated quinazolinone derivative, a crucial heterocyclic scaffold in modern organic synthesis. This compound matters as a versatile and valuable building block for pharmaceutical research and development, particularly in the creation of kinase inhibitors and other targeted therapeutic agents. It is primarily needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for lead optimization and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Probe Development: Used to create tool compounds for studying specific enzyme functions and signaling pathways.
• Agrochemical Research: Serves as a building block for developing new active ingredients with herbicidal or fungicidal properties.
• Material Science: Investigated as a monomer or precursor for constructing organic electronic materials and advanced polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and novel heterocycle synthesis.

Basic Information

Product Name	2-Chloro-7-Iodoquinazolin-4(3H)-One
CAS No.	744229-16-1
Molecular Formula	C8H4ClIN2O
Molecular Weight	306.49 g/mol
Synonyms	4(3H)-Quinazolinone, 2-chloro-7-iodo-; 2-Chloro-7-iodo-4(3H)-quinazolinone; 2-Chloro-7-iodoquinazolin-4-ol; 7-Iodo-2-chloroquinazolin-4(3H)-one; 744229-16-1; 2-Chloro-7-iodo-3,4-dihydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-7-Iodoquinazolin-4(3H)-One is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for research chemicals. Comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, is performed. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.