Description

4,6-Methanocyclopenta[B]Pyran-2(3H)-One,Hexahydro-5-Hydroxy-4A,5-Dimethyl-,(4S,4As,5S,6R,7As)-(9Ci) is a complex, stereochemically defined organic compound with a fused cyclopenta-pyranone structure. This molecule is of significant interest as a key chiral intermediate or building block in advanced organic synthesis, particularly for the development of pharmaceuticals and fine chemicals. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers engaged in the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system or metabolic disorders.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Natural Product Analog Synthesis: Used in the research and development of analogs to naturally occurring compounds with fused polycyclic structures.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new chemical entities.
• Chemical Biology Research: Acts as a probe or precursor in the study of biological pathways and enzyme interactions.
• Fine Chemical Production: Incorporated into the manufacture of high-value, low-volume specialty chemicals for advanced material science applications.

Basic Information

Product Name	4,6-Methanocyclopenta[B]Pyran-2(3H)-One,Hexahydro-5-Hydroxy-4A,5-Dimethyl-,(4S,4As,5S,6R,7As)-(9Ci)
CAS No.	744208-27-3
Molecular Formula	C11H16O3
Molecular Weight	196.24 g/mol
Synonyms	Hexahydro-5-hydroxy-4a,5-dimethyl-4,6-methanocyclopenta[b]pyran-2(3H)-one; (4S,4aS,5S,6R,7aS)-Hexahydro-5-hydroxy-4a,5-dimethyl-4,6-methanocyclopenta[b]pyran-2(3H)-one; 4,6-Methanocyclopenta[b]pyran-2(3H)-one, hexahydro-5-hydroxy-4a,5-dimethyl-, (4S,4aS,5S,6R,7aS)-; (4S,4aS,5S,6R,7aS)-4,6-Methanocyclopenta[b]pyran-2(3H)-one, hexahydro-5-hydroxy-4a,5-dimethyl-; A stereoisomer of a fused cyclopenta-pyranone.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.