Description

2-[(E)-2-(3-Nitrophenyl)Ethenyl]Quinazolin-4(3H)-One is a specialized quinazolinone derivative featuring a conjugated ethenyl bridge to a nitrophenyl group. This compound is valued as a versatile pharmaceutical intermediate and a key building block in organic synthesis for creating complex molecular architectures. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential electron-transport or emissive layer material due to its conjugated, rigid structure.
• Fluorescent Probe Synthesis: Employed in creating dyes and sensors for biochemical and analytical applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.
• Material Science: Investigated as a monomer or additive for advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	2-[(E)-2-(3-Nitrophenyl)Ethenyl]Quinazolin-4(3H)-One
CAS No.	743477-75-0
Molecular Formula	C₁₆H₁₁N₃O₃
Molecular Weight	293.28 g/mol
Synonyms	4(3H)-Quinazolinone, 2-[(1E)-2-(3-nitrophenyl)ethenyl]-; (E)-2-(2-(3-Nitrophenyl)vinyl)quinazolin-4(3H)-one; 2-[(E)-2-(3-Nitrophenyl)vinyl]-4(3H)-quinazolinone; 2-Styrylquinazolin-4(3H)-one derivative; 3-Nitrostyrylquinazolinone; Light-sensitive quinazolinone intermediate; CAS 743477-75-0
EINECS	Contact for details

Quality Control

Our 2-[(E)-2-(3-Nitrophenyl)Ethenyl]Quinazolin-4(3H)-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets precise customer specifications and high-purity standards for research and production. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.