Description

2-Trifluoromethyl-5,6,7,8-Tetrahydro-[1,7]Naphthyridine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the electron-deficient trifluoromethyl group and the hydrogenated naphthyridine scaffold, which is pivotal for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the design and synthesis of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a precursor for the development of specialty chemicals, ligands, and functional materials.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Catalyst and Ligand Development: Utilized in the synthesis of novel ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects.

Basic Information

Product Name	2-Trifluoromethyl-5,6,7,8-Tetrahydro-[1,7]Naphthyridine
CAS No.	741737-13-3
Molecular Formula	C9H9F3N2
Molecular Weight	202.18 g/mol
Synonyms	2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine; 5,6,7,8-Tetrahydro-2-(trifluoromethyl)-1,7-naphthyridine; 2-Trifluoromethyl-5,6,7,8-tetrahydro-1,7-naphthyridine; 1,7-Naphthyridine, 5,6,7,8-tetrahydro-2-(trifluoromethyl)-; 741737-13-3; 2-Trifluoromethyl-5,6,7,8-tetrahydro[1,7]naphthyridine
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-5,6,7,8-Tetrahydro-[1,7]Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong alkali and fluorides; keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.