Description

2-Chloro-6-Hydroxyquinoline-3-Carbaldehyde is a versatile and highly functionalized quinoline derivative that serves as a critical synthetic intermediate. Its unique molecular scaffold, featuring both aldehyde and halogen substituents, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors, antimicrobial agents, and anti-inflammatory compounds.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and pesticides by acting as a core structure for bioactive molecule design.
• Organic Synthesis Building Block: The reactive aldehyde and chloro groups facilitate further functionalization through cross-coupling, condensation, and cyclization reactions.
• Coordination Chemistry & Ligand Synthesis: Serves as a starting material for creating chelating ligands used in catalysis and material science.
• Dye & Pigment Intermediate: Utilized in the research and development of advanced quinoline-based dyes and functional pigments.
• Material Science Research: Investigated as a monomer or precursor for organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-6-Hydroxyquinoline-3-Carbaldehyde
CAS No.	741705-20-4
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	2-Chloro-6-hydroxyquinoline-3-carboxaldehyde; 3-Formyl-2-chloro-6-hydroxyquinoline; 6-Hydroxy-2-chloroquinoline-3-carbaldehyde; 2-Chloro-6-hydroxy-3-quinolinecarboxaldehyde; Quinoline-3-carbaldehyde, 2-chloro-6-hydroxy-; 2-Chloro-6-hydroxyquinoline-3-carboxaldehyde (CAS 741705-20-4)
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Hydroxyquinoline-3-Carbaldehyde is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.