Description

Spiro[Furo[3,4-C]Pyridine-3(1H),4'-Piperidine],6-Fluoro- is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic and heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers engaged in innovative drug development programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates targeting neurological disorders.
• CNS Drug Research: Used in the synthesis of potential therapeutics for conditions such as depression, anxiety, and schizophrenia.
• Oncology Research: Serves as a scaffold for creating novel small-molecule inhibitors and targeted cancer therapies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and reference standards.

Basic Information

Product Name	Spiro[Furo[3,4-C]Pyridine-3(1H),4'-Piperidine],6-Fluoro-
CAS No.	741683-18-1
Molecular Formula	C12H13FN2O
Molecular Weight	220.25 g/mol
Synonyms	6-Fluoro-1'H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]; 6-Fluoro-1,4-dihydrospiro[furo[3,4-c]pyridine-3,4'-piperidine]; 6-Fluoro-3,4-dihydro-1'H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]; 6-Fluoro-spiro(furo[3,4-c]pyridine-3(1H),4'-piperidine); Spiro(furo[3,4-c]pyridine-3(1H),4'-piperidine), 6-fluoro-; 741683-18-1
EINECS	Contact for details

Quality Control

Every batch of Spiro[Furo[3,4-C]Pyridine-3(1H),4'-Piperidine],6-Fluoro- is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.