Description

3,4-Dihydro-3-(4-Piperidinyl)-2(1H)-Quinolinone is a high-purity advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers seeking reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of investigational new drugs, especially those targeting neurological receptors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing complex molecules with potential therapeutic activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3,4-Dihydro-3-(4-Piperidinyl)-2(1H)-Quinolinone
CAS No.	741235-48-3
Molecular Formula	C14H16N2O
Molecular Weight	228.29 g/mol
Synonyms	3-(4-Piperidinyl)-3,4-dihydro-2(1H)-quinolinone; 3-(Piperidin-4-yl)-1,2,3,4-tetrahydroquinolin-2-one; 2(1H)-Quinolinone, 3,4-dihydro-3-(4-piperidinyl)-; 3-(4-Piperidyl)-3,4-dihydro-2(1H)-quinolinone; 3-Piperidin-4-yl-3,4-dihydro-1H-quinolin-2-one; 741235-48-3; UNII-9J2J8Q8V8R
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-3-(4-Piperidinyl)-2(1H)-Quinolinone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.