Description

1H-Imidazole,4-[(3R)-3-Pyrrolidinylmethyl]-(9Ci) is a high-purity, chiral imidazole derivative with a CAS Registry Number of 738578-40-0. This compound is a valuable synthetic intermediate, prized for its role in constructing complex molecules with specific stereochemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries. Its structural features make it a key building block for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the specific stereochemistry of the molecule can influence biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: The imidazole moiety can be utilized in the development of linkers and probes for biochemical and diagnostic applications.
• Academic & Contract Research: Essential for organic synthesis research in universities and CROs (Contract Research Organizations) exploring new chemical entities and reaction pathways.

Basic Information

Product Name	1H-Imidazole,4-[(3R)-3-Pyrrolidinylmethyl]-(9Ci)
CAS No.	738578-40-0
Molecular Formula	C8H13N3
Molecular Weight	151.21 g/mol
Synonyms	(R)-4-(Pyrrolidin-3-ylmethyl)-1H-imidazole; 4-[(3R)-3-Pyrrolidinylmethyl]-1H-imidazole; 738578-40-0; (R)-1H-Imidazole, 4-(3-pyrrolidinylmethyl)-; 4-((R)-Pyrrolidin-3-ylmethyl)-1H-imidazole; SCHEMBL2180426; A1-008/31502055
EINECS	Contact for details

Quality Control

Our 1H-Imidazole,4-[(3R)-3-Pyrrolidinylmethyl]-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as chiral purity, chemical assay, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.