Description

Isobenzofuran, 1,4,5,6,7,7A-Hexahydro-1-Phenyl-, (1R,7Ar)-Rel- (9Ci) is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique fused bicyclic structure with defined stereochemistry makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its structural complexity can contribute to unique biological activity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Acts as a building block for the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of novel polymers with specific optical or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, particularly in cycloaddition and ring-opening reactions.

Basic Information

Product Name	Isobenzofuran, 1,4,5,6,7,7A-Hexahydro-1-Phenyl-, (1R,7Ar)-Rel- (9Ci)
CAS No.	737767-33-8
Molecular Formula	C14H16O
Molecular Weight	200.28 g/mol
Synonyms	rel-(1R,7aR)-1,4,5,6,7,7a-Hexahydro-1-phenylisobenzofuran; 1-Phenyl-1,4,5,6,7,7a-hexahydroisobenzofuran; (1R,7aR)-1-Phenyloctahydroisobenzofuran; 737767-33-8; 1-Phenyl-1,4,5,6,7,7a-hexahydro-2-benzofuran; rel-(1R,7aR)-1-Phenyl-1,4,5,6,7,7a-hexahydro-2-benzofuran
EINECS	Contact for details

Quality Control

Our Isobenzofuran, 1,4,5,6,7,7A-Hexahydro-1-Phenyl-, (1R,7Ar)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95%
Enantiomeric Excess (Chiral HPLC)	≥ 98% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.