Description

8-Bromo-6-Chloro-9-Methyl-9H-Purine is a halogenated purine derivative, a crucial building block in medicinal chemistry and pharmaceutical research. Its unique substitution pattern makes it a versatile intermediate for synthesizing novel nucleoside analogs and targeted small molecule libraries. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of antiviral and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel purine-based drug candidates targeting various diseases.
• Antiviral Agent Research: Used as a core scaffold for developing nucleoside analogs with potential activity against viral polymerases.
• Oncology Research: Serves as a building block for kinase inhibitors and other targeted cancer therapies.
• Biochemical Tool Compound: Employed in enzymatic studies and as a probe to investigate purinergic signaling pathways.
• Agrochemical Intermediate: Potential use in the synthesis of new plant growth regulators or pesticides.
• Academic & Contract Research: Fundamental material for synthetic organic chemistry and methodology development in heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-6-Chloro-9-Methyl-9H-Purine
CAS No.	736142-86-2
Molecular Formula	C6H4BrClN4
Molecular Weight	247.48 g/mol
Synonyms	8-Bromo-6-chloro-9-methylpurine; 9-Methyl-8-bromo-6-chloropurine; 6-Chloro-8-bromo-9-methyl-9H-purine; 8-Bromo-6-chloro-9-methyl-9H-purine; Purine, 8-bromo-6-chloro-9-methyl-; 8-Bromo-6-chloro-9-methylpurine (CAS 736142-86-2); 6-Chloro-8-bromo-9-methylpurine
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Chloro-9-Methyl-9H-Purine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.