Description

2-Azabicyclo[2.2.2]Octane-3-Carboxylicacid,Methylester,(3S)-(9Ci) is a high-value, stereochemically defined bicyclic lactam derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid, three-dimensional scaffold is essential for constructing complex molecular architectures with precise spatial orientation, directly impacting the efficacy and selectivity of final products. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential central nervous system (CNS) agents and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in neuroscience and therapeutic areas requiring complex, constrained molecular frameworks.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific 3D structure is crucial for biological activity.
• Catalyst & Ligand Development: Serves as a precursor for designing novel chiral catalysts and ligands used in asymmetric synthesis to produce enantiomerically pure compounds.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, enabling the exploration of new synthetic routes to complex nitrogen-containing heterocycles.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals where the 2-azabicyclo[2.2.2]octane core structure is required.

Basic Information

Product Name	2-Azabicyclo[2.2.2]Octane-3-Carboxylicacid,Methylester,(3S)-(9Ci)
CAS No.	736111-77-6
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(3S)-2-Azabicyclo[2.2.2]octane-3-carboxylic acid methyl ester; Methyl (3S)-2-azabicyclo[2.2.2]octane-3-carboxylate; (S)-Methyl 2-azabicyclo[2.2.2]octane-3-carboxylate; 2-Azabicyclo[2.2.2]octane-3-carboxylic acid, methyl ester, (3S)-; (3S)-3-(Methoxycarbonyl)-2-azabicyclo[2.2.2]octane; (S)-3-Methoxycarbonyl-2-azabicyclo[2.2.2]octane; (3S)-Methyl 2-azabicyclo[2.2.2]octane-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Azabicyclo[2.2.2]Octane-3-Carboxylicacid,Methylester,(3S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.