Description

cis-4-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, synthetically derived organic compound featuring a cyclohexane carboxylic acid core substituted with a 4-fluorophenyl ketone moiety. This specific stereochemistry and functional group arrangement make it a valuable and versatile advanced pharmaceutical intermediate (API intermediate) and a critical building block in modern organic synthesis. It is primarily utilized by research institutions and industrial manufacturers engaged in the development and production of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and inflammatory conditions.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Organic Synthesis & Research: Used in academic and industrial R&D for constructing complex molecular architectures, studying structure-activity relationships (SAR), and developing novel synthetic methodologies.
• Ligand & Catalyst Development: The carboxylic acid and ketone functionalities allow for its use in creating specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Potential application as a monomer or modifying agent in the synthesis of specialty polymers and advanced materials with tailored properties.

Basic Information

Item	Details
Product Name	cis-4-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735275-61-3
Molecular Formula	C15H17FO3
Molecular Weight	264.30 g/mol
Synonyms	4-[(4-Fluorobenzoyl)methyl]cyclohexanecarboxylic acid (cis-); cis-4-(2-(4-Fluorophenyl)-2-oxoethyl)cyclohexanecarboxylic acid; (1r,4r)-4-[2-(4-Fluorophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; 4-(4-Fluorophenacyl)cyclohexanecarboxylic acid; 735275-61-3; cis-4-(4-Fluorophenacyl)cyclohexanecarboxylic Acid; 4-(4-Fluorobenzoylmethyl)cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our cis-4-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and consistent stereochemical integrity. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area %)
cis-Isomer Content (HPLC/Chiral)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.