Description

cis-3-[2-(3-Iodophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, synthetically derived iodinated carboxylic acid building block. This compound is valued for its unique molecular architecture, which combines a cyclohexane carboxylic acid core with a 3-iodoacetophenone moiety, making it a versatile intermediate for advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in medicinal chemistry programs targeting novel therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for non-steroidal anti-inflammatory drugs (NSAIDs) and other target molecules.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators where the iodine atom and ketone functionality allow for further selective derivatization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags due to the reactivity of the iodine atom in cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	cis-3-[2-(3-Iodophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735275-38-4
Molecular Formula	C15H17IO3
Molecular Weight	372.20 g/mol
Synonyms	3-[2-(3-Iodophenyl)-2-oxoethyl]cyclohexanecarboxylic acid (cis-); cis-3-(2-(3-Iodobenzoyl)ethyl)cyclohexanecarboxylic Acid; (1r,3s)-3-[2-(3-iodophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; 735275-38-4; cis-3-(2-(3-Iodophenyl)-2-oxoethyl)cyclohexanecarboxylic acid; 3-(2-(3-Iodophenyl)-2-oxoethyl)cyclohexanecarboxylic acid, cis-; Cyclohexanecarboxylic acid, 3-[2-(3-iodophenyl)-2-oxoethyl]-, cis-
EINECS	Contact for details

Quality Control

Our cis-3-[2-(3-Iodophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.