Description

trans-2-[2-(4-Iodophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific iodinated aromatic and carboxylic acid functional groups. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) for targeted therapies.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex molecular architectures via its reactive ketone and carboxylic acid moieties.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Bioconjugation Chemistry: Potential use in developing antibody-drug conjugates (ADCs) or other targeted drug delivery systems.

Basic Information

Product Name	trans-2-[2-(4-Iodophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735274-97-2
Molecular Formula	C15H17IO3
Molecular Weight	372.20 g/mol
Synonyms	2-[(4-Iodobenzoyl)methyl]cyclohexanecarboxylic acid (trans); trans-2-[(4-Iodobenzoyl)methyl]cyclohexanecarboxylic acid; (1R,2R)-2-[2-(4-Iodophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; (1S,2S)-2-[2-(4-Iodophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; CAS 735274-97-2; 735274-97-2; 2-(2-(4-Iodophenyl)-2-oxoethyl)cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our trans-2-[2-(4-Iodophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.