Description

trans-2-(2-Cyanobenzoyl)Cyclopentane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potent API candidates, especially for central nervous system (CNS) and anti-inflammatory drugs.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex molecular architectures, leveraging its benzoyl and carboxylic acid functionalities.
• Preclinical & Clinical Development: Serves as a critical starting material or intermediate in the scale-up process for drug substances undergoing regulatory evaluation.
• Process Chemistry: Employed in route scouting and optimization studies to develop efficient, scalable, and cost-effective manufacturing processes for target molecules.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	trans-2-(2-Cyanobenzoyl)Cyclopentane-1-Carboxylic Acid
CAS No.	733740-85-7
Molecular Formula	C14H13NO3
Molecular Weight	243.26 g/mol
Synonyms	(1R,2S)-2-(2-Cyanobenzoyl)cyclopentane-1-carboxylic acid; (1S,2R)-2-(2-Cyanobenzoyl)cyclopentane-1-carboxylic acid; trans-2-(2-Cyanobenzoyl)-1-cyclopentanecarboxylic Acid; 2-(2-Cyanobenzoyl)cyclopentanecarboxylic Acid (trans-); 733740-85-7; 2-Cyanobenzoyl Cyclopentane Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our trans-2-(2-Cyanobenzoyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.