Description

cis-3-[2-Oxo-2-(3-Trifluoromethylphenyl)Ethyl]Cyclopentane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific cyclopentane carboxylic acid structure and trifluoromethylphenyl ketone moiety. This compound is critical for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise molecular architecture is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of proprietary drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Serves as a sophisticated synthon for developing new-generation herbicides and pesticides, leveraging the stability of the trifluoromethyl group.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex organic molecules, facilitating studies in medicinal chemistry and material science.
• Ligand and Catalyst Development: The carboxylic acid and ketone functionalities make it a candidate for developing chiral ligands or metal-organic frameworks (MOFs).
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and impurity profiling in API manufacturing.

Basic Information

Item	Detail
Product Name	cis-3-[2-Oxo-2-(3-Trifluoromethylphenyl)Ethyl]Cyclopentane-1-Carboxylic Acid
CAS No.	733740-46-0
Molecular Formula	C15H15F3O3
Molecular Weight	300.28 g/mol
Synonyms	3-[2-Oxo-2-[3-(trifluoromethyl)phenyl]ethyl]cyclopentane-1-carboxylic acid (cis-); (1R,3S)-3-[2-Oxo-2-[3-(trifluoromethyl)phenyl]ethyl]cyclopentane-1-carboxylic acid; (1S,3R)-3-[2-Oxo-2-[3-(trifluoromethyl)phenyl]ethyl]cyclopentane-1-carboxylic acid; cis-3-(2-Oxo-2-(3-(trifluoromethyl)phenyl)ethyl)cyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 3-[2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl]-, cis-; 733740-46-0; 3-(2-Oxo-2-(3-trifluoromethylphenyl)ethyl)cyclopentane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of cis-3-[2-Oxo-2-(3-Trifluoromethylphenyl)Ethyl]Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supported by comprehensive Certificates of Analysis (COA), which detail key parameters such as assay, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable, ensuring reliability for critical pharmaceutical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (cis-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.