Description

4-Amino-5-[2-(4-Methylphenyl)Quinolin-4-Yl]-4H-1,2,4-Triazole-3-Thiol is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical and agrochemical research. Its complex molecular architecture, featuring fused quinoline and triazole-thiol moieties, makes it a valuable scaffold for developing novel active ingredients. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly for synthesizing potential drug candidates and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for creating specialized ligands in catalysis and functional materials.
• Bioconjugation Chemistry: The thiol and amino groups provide handles for protein labeling and probe development.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Amino-5-[2-(4-Methylphenyl)Quinolin-4-Yl]-4H-1,2,4-Triazole-3-Thiol
CAS No.	733030-64-3
Molecular Formula	C18H15N5S
Molecular Weight	333.41 g/mol
Synonyms	4-Amino-5-(2-p-tolylquinolin-4-yl)-4H-1,2,4-triazole-3-thiol; 4-Amino-5-[2-(4-methylphenyl)-4-quinolinyl]-1,2,4-triazole-3-thiol; 4-Amino-5-(2-(4-methylphenyl)quinolin-4-yl)-4H-1,2,4-triazole-3-thiol; 733030-64-3; 4H-1,2,4-Triazole-3-thiol, 4-amino-5-[2-(4-methylphenyl)-4-quinolinyl]-; AKOS005258065; 4-Amino-5-(2-(p-tolyl)quinolin-4-yl)-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 4-Amino-5-[2-(4-Methylphenyl)Quinolin-4-Yl]-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen in a sealed container.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.