Description

(8-Benzyl-2,4-Dioxo-1,3,8-Triaza-Spiro[4.5]Dec-3-Yl)-Acetic Acid CAS NO 732926-20-4 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and triaza structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Development: Incorporated into the core structure of target APIs, especially those with spirocyclic motifs for enhanced metabolic stability and receptor selectivity.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific development projects.
• Bioconjugation Chemistry: The acetic acid moiety can be utilized for conjugation reactions, linking the pharmacophore to carriers or other functional molecules.
• Chemical Biology Probes: Potential use in creating specialized probes for studying enzyme mechanisms or biological pathways.

Basic Information

Product Name	(8-Benzyl-2,4-Dioxo-1,3,8-Triaza-Spiro[4.5]Dec-3-Yl)-Acetic Acid
CAS No.	732926-20-4
Molecular Formula	C16H19N3O4
Molecular Weight	317.34 g/mol
Synonyms	2-(8-Benzyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)acetic acid; 3-(Carboxymethyl)-8-benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione; (8-Benzyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)acetic acid; 732926-20-4; 8-Benzyl-3-(carboxymethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione; Spiro[4.5]decane-2,4-dione derivative
EINECS	Contact for details

Quality Control

Our (8-Benzyl-2,4-Dioxo-1,3,8-Triaza-Spiro[4.5]Dec-3-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.