Description

2-(4-(tert-Butoxycarbonyl)Phenyl)Acetic Acid is a high-purity, protected phenylacetic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the versatile tert-butoxycarbonyl (Boc) protecting group, which allows for selective deprotection under mild acidic conditions, enabling the synthesis of complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active pharmaceutical ingredients (APIs), peptide mimetics, and novel organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing phenylacetic acid or benzylamine motifs.
• Peptide Chemistry: Used as a protected amino acid derivative or side-chain component in the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators that require a protected carboxylic acid functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands, metal-organic frameworks (MOFs), and organocatalysts.
• Material Science Research: Intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(4-(tert-Butoxycarbonyl)Phenyl)Acetic Acid
CAS No.	732308-82-6
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	4-(Boc)Phenylacetic Acid; 2-[4-[(1,1-Dimethylethoxy)carbonyl]phenyl]acetic Acid; 2-(4-((tert-Butoxycarbonyl)phenyl)acetic Acid; 4-(tert-Butoxycarbonyl)benzeneacetic Acid; Boc-Phenylacetic Acid; (4-(tert-Butoxycarbonyl)phenyl)acetic Acid; p-(tert-Butoxycarbonyl)phenylacetic Acid; 2-(4-Carboxybutoxy)phenylacetic Acid (related isomer)
EINECS	Contact for details

Quality Control

Our 2-(4-(tert-Butoxycarbonyl)Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.