Description

(R)-6-Fluoro-2,3-Dihydro-1H-Inden-1-Aminehydrochloride is a high-purity chiral amine building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and advanced fine chemical manufacturers engaged in the development of enantiomerically pure therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in neurological and psychiatric research.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(R)-6-Fluoro-2,3-Dihydro-1H-Inden-1-Aminehydrochloride
CAS No.	731859-02-2
Molecular Formula	C9H11ClFN
Molecular Weight	187.64 g/mol
Synonyms	(1R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride; (R)-6-Fluoroindan-1-amine hydrochloride; (R)-1-Amino-6-fluoroindane hydrochloride; 6-Fluoro-(1R)-indan-1-ylamine hydrochloride; (R)-6-Fluoro-1-indanamine hydrochloride; (1R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine HCl; (R)-1-Amino-6-fluoro-2,3-dihydro-1H-indene hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-6-Fluoro-2,3-Dihydro-1H-Inden-1-Aminehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.