Description

(1S,2S)-Rel-2-(4-Hydroxyphenyl)Cyclopropane-1-Carboxylic Acid is a high-purity chiral cyclopropane derivative, a key structural motif in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile and critical building block for pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a chiral precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and metabolic conditions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane ring can impart specific biological activity and stability.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Building Block: Employed in the multi-step synthesis of complex natural products, flavors, fragrances, and advanced materials.
• Bioconjugation and Probe Synthesis: The carboxylic acid and phenolic hydroxyl groups provide handles for conjugation, useful in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	(1S,2S)-Rel-2-(4-Hydroxyphenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	731810-73-4
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	(1S,2S)-2-(4-Hydroxyphenyl)cyclopropanecarboxylic Acid; rel-(1S,2S)-2-(4-Hydroxyphenyl)cyclopropanecarboxylic Acid; 2-(4-Hydroxyphenyl)cyclopropanecarboxylic Acid (1S,2S)-rel-; (1S,2S)-2-(p-Hydroxyphenyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-(4-hydroxyphenyl)-, (1S,2S)-rel-; 731810-73-4; (1S,2S)-HCCA
EINECS	Contact for details

Quality Control

Our (1S,2S)-Rel-2-(4-Hydroxyphenyl)Cyclopropane-1-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.