Description

1H-Isoindole-1-Carboxylicacid,Octahydro-,(1R,3As,7As)-(9Ci) is a high-purity, stereochemically defined bicyclic heterocyclic building block. This compound is a critical chiral intermediate in modern pharmaceutical synthesis, enabling the development of complex, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Serves as a versatile scaffold for constructing complex molecular architectures with defined stereochemistry.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals and advanced materials.
• Process Chemistry Development: Used to develop and scale up efficient synthetic routes for potential commercial APIs.

Basic Information

Product Name	1H-Isoindole-1-Carboxylicacid,Octahydro-,(1R,3As,7As)-(9Ci)
CAS No.	729556-25-6
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(1R,3aS,7aS)-Octahydro-1H-isoindole-1-carboxylic acid; (1R,3aS,7aS)-1,2,3,3a,4,5,7,7a-Octahydroisoindole-1-carboxylic acid; (1R,3aS,7aS)-Octahydroisoindole-1-carboxylic acid; (1R,3aS,7aS)-Hexahydro-1H-isoindole-1-carboxylic acid; 1H-Isoindole-1-carboxylic acid, octahydro-, (1R,3aS,7aS)-; 729556-25-6; (1R,3aS,7aS)-1-Carboxyhexahydroisoindole
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1-Carboxylicacid,Octahydro-,(1R,3As,7As)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.