Description

Benzamide, 2,4-Difluoro-n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)- (9Ci) is a high-purity, specialized heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both a difluorobenzamide moiety and a 5-methyl-1,3,4-thiadiazole ring, makes it a valuable intermediate for developing novel active ingredients. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. Its precise structure enables the fine-tuning of biological activity and physicochemical properties in target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of new chemical entities (NCEs) for drug discovery programs, particularly for candidates targeting infectious diseases or metabolic disorders.
• Agrochemical Research: Used as a core scaffold for developing next-generation herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiadiazole and fluorinated aromatic systems.
• Material Science Chemistry: Serves as a monomer or functional additive in the research of specialty polymers and advanced materials requiring specific thermal or chemical resistance.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, or activity-based probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	Benzamide, 2,4-Difluoro-n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)- (9Ci)
CAS No.	728009-78-7
Molecular Formula	C10H7F2N3OS
Molecular Weight	255.24 g/mol
Synonyms	2,4-Difluoro-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzamide; N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2,4-difluorobenzamide; 2,4-Difluorobenzoic acid (5-methyl-1,3,4-thiadiazol-2-yl)amide; 728009-78-7; 2,4-Difluoro-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzamide (9CI); Benzamide, 2,4-difluoro-N-(5-methyl-1,3,4-thiadiazol-2-yl)-
EINECS	Contact for details

Quality Control

Our production of Benzamide, 2,4-Difluoro-n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects with material produced under quality systems aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.