Description

tert-Butyl-5-Methoxy-2,3-Dihydropyrrolo[2,3-C-]Pyridine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new pharmacophores based on the dihydropyrrolopyridine core.
• API Synthesis: Integral in constructing the core scaffold for potential APIs, where the tert-butyloxycarbonyl (Boc) protecting group and methoxy substitution offer strategic handles for further functionalization.
• Contract Manufacturing: Supplied to CDMOs for scale-up production under current Good Manufacturing Practice (cGMP) conditions for clinical trial material and commercial manufacturing.
• Chemical Biology: Can be utilized as a molecular probe or a tagged ligand in biochemical assays to study protein-ligand interactions.

Basic Information

Product Name	tert-Butyl-5-Methoxy-2,3-Dihydropyrrolo[2,3-C-]Pyridine-1-Carboxylate
CAS No.	727993-74-0
Molecular Formula	C13H18N2O3
Molecular Weight	250.30 g/mol
Synonyms	1-Boc-5-Methoxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine; 5-Methoxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-methoxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-1-carboxylate; 727993-74-0; 1H-Pyrrolo[2,3-c]pyridine-1-carboxylic acid, 2,3-dihydro-5-methoxy-, 1,1-dimethylethyl ester; Boc-5-Methoxy-2,3-dihydropyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl-5-Methoxy-2,3-Dihydropyrrolo[2,3-C-]Pyridine-1-Carboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.