Description

8-Ethoxy-4,4,6-Trimethyl-5,6-Dihydro-4H-Pyrrolo-[3,2,1-Ij]Quinoline-1,2-Dione is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development for therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Process Development & Scale-Up: Serves as a critical intermediate for optimizing synthetic routes from laboratory to pilot and commercial scale.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic chemistry and pharmacology projects.
• Fine Chemical Synthesis: A precursor for creating other complex, value-added specialty chemicals with specific biological activities.

Basic Information

Product Name	8-Ethoxy-4,4,6-Trimethyl-5,6-Dihydro-4H-Pyrrolo-[3,2,1-Ij]Quinoline-1,2-Dione
CAS No.	727661-21-4
Molecular Formula	C₁₈H₂₁NO₃
Molecular Weight	299.37 g/mol
Synonyms	8-Ethoxy-4,4,6-trimethyl-4H,5H,6H-pyrrolo[3,2,1-ij]quinoline-1,2-dione; 727661-21-4; Pyrroloquinoline-1,2-dione, 8-ethoxy-4,4,6-trimethyl-5,6-dihydro-4H-; 4H-Pyrrolo[3,2,1-ij]quinoline-1,2-dione, 8-ethoxy-4,4,6-trimethyl-5,6-dihydro-; 5,6-Dihydro-8-ethoxy-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione
EINECS	Contact for details

Quality Control

Our 8-Ethoxy-4,4,6-Trimethyl-5,6-Dihydro-4H-Pyrrolo-[3,2,1-Ij]Quinoline-1,2-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.