Description

(4-Fluoro-Phenylamino)-Thiophen-2-Yl-Acetic Acid is a specialized organic building block featuring a unique molecular scaffold combining fluorinated aniline and thiophene acetic acid motifs. This compound matters as a high-value intermediate for pharmaceutical research and development, enabling the synthesis of novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its distinct pharmacophore into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and fluorinated aniline structures.
• Material Science Precursor: Acts as a building block for advanced organic electronic materials, such as organic semiconductors and conductive polymers, due to the electron-rich thiophene unit.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API (Active Pharmaceutical Ingredient) development.

Basic Information

Product Name	(4-Fluoro-Phenylamino)-Thiophen-2-Yl-Acetic Acid
CAS No.	725253-20-3
Molecular Formula	C12H10FNO2S
Molecular Weight	251.28 g/mol
Synonyms	2-[(4-Fluorophenyl)amino]-2-thiophen-2-ylacetic acid; 2-((4-Fluorophenyl)amino)-2-(thiophen-2-yl)acetic acid; (4-Fluorophenylamino)(2-thienyl)acetic acid; 2-(Thiophen-2-yl)-2-[(4-fluorophenyl)amino]acetic acid; α-[(4-Fluorophenyl)amino]-2-thiopheneacetic acid; 725253-20-3; (4-Fluoroanilino)(2-thienyl)acetic acid
EINECS	Contact for details

Quality Control

Our (4-Fluoro-Phenylamino)-Thiophen-2-Yl-Acetic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.