Description

1H-Benzimidazole-1-Carboxylicacid,5-(Hydroxymethyl)-,1,1-Dimethylethylester is a specialized organic compound belonging to the benzimidazole class, serving as a key protected intermediate in advanced synthetic chemistry. Its core value lies in enabling the controlled synthesis of complex molecules, particularly in pharmaceutical research and development. This product is essential for R&D chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to build novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides.
• Fine Chemical Production: Serves as a protected synthon in the multi-step synthesis of complex organic molecules for specialty applications.
• Bioconjugation & Linker Chemistry: The reactive ester and hydroxymethyl groups make it suitable for creating chemical linkers in bioconjugation and prodrug strategies.
• Material Science Research: Potential precursor for the development of organic electronic materials or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in university and corporate laboratories.

Basic Information

Product Name	1H-Benzimidazole-1-Carboxylicacid,5-(Hydroxymethyl)-,1,1-Dimethylethylester
CAS No.	725237-71-8
Molecular Formula	C14H18N2O3
Molecular Weight	262.31 g/mol
Synonyms	5-(Hydroxymethyl)-1H-benzimidazole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 5-(hydroxymethyl)-1H-benzimidazole-1-carboxylate; 1-(tert-Butoxycarbonyl)-5-(hydroxymethyl)benzimidazole; 5-(Hydroxymethyl)-1-Boc-benzimidazole; 1-Boc-5-(hydroxymethyl)benzimidazole; 1H-Benzimidazole-1-carboxylic acid, 5-(hydroxymethyl)-, 1,1-dimethylethyl ester; 725237-71-8; Boc-5-(hydroxymethyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-1-Carboxylicacid,5-(Hydroxymethyl)-,1,1-Dimethylethylester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support customers requiring material for cGMP intermediates or advanced non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.