Description

8-Bromo-7-Fluoro-2-Methoxy-1,5-Naphthyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique halogenated and methoxylated structure, which provides multiple reactive sites for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the creation of organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Cross-Coupling Reactions: The bromo and fluoro substituents make it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis: A valuable building block for generating diverse compound libraries in high-throughput screening for drug discovery.

Basic Information

Product Name	8-Bromo-7-Fluoro-2-Methoxy-1,5-Naphthyridine
CAS No.	724788-70-9
Molecular Formula	C9H6BrFN2O
Molecular Weight	257.06 g/mol
Synonyms	8-Bromo-7-fluoro-2-methoxy-1,5-naphthyridine; 1,5-Naphthyridine, 8-bromo-7-fluoro-2-methoxy-; 2-Methoxy-8-bromo-7-fluoro-1,5-naphthyridine; 7-Fluoro-8-bromo-2-methoxy-1,5-naphthyridine; 8-Bromo-7-fluoro-2-methoxy-[1,5]naphthyridine; BRN 12501613; AKOS005258204
EINECS	Contact for details

Quality Control

Our 8-Bromo-7-Fluoro-2-Methoxy-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and other high-value chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.