Description

3-Chloro-6-Methoxy-[1,5]-Naphthyridin-4-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and agrochemicals, where its unique naphthyridine scaffold enables the construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of potential drug candidates, particularly in kinase inhibitor and antimicrobial discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for catalysts or functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library production.

Basic Information

Product Name	3-Chloro-6-Methoxy-[1,5]-Naphthyridin-4-Ol
CAS No.	724787-12-6
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	4-Hydroxy-3-chloro-6-methoxy-[1,5]naphthyridine; 3-Chloro-6-methoxy-1,5-naphthyridin-4-ol; 3-Chloro-6-methoxy-1,5-naphthyridin-4(1H)-one; 724787-12-6; 3-Chloro-6-methoxy-[1,5]naphthyridin-4-ol
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Methoxy-[1,5]-Naphthyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.