Description

1-(((tert-Butoxycarbonyl)Amino)Methyl)Spiro[2.5]Octane-1-Carboxylic Acid is a high-value, multifunctional spirocyclic building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. Its unique spiro[2.5]octane scaffold, protected by a Boc (tert-butoxycarbonyl) group, makes it an essential intermediate for medicinal chemistry, peptide mimetics, and materials science applications where steric control and three-dimensional complexity are paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Peptidomimetic Chemistry: Used to introduce constrained, spirocyclic motifs into peptide backbones to enhance metabolic stability and receptor selectivity.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and protein-protein interactions.
• Agrochemical Research: Employed in the discovery of new pesticides and herbicides that leverage its unique three-dimensional structure.
• Material Science: A potential monomer or cross-linker for creating specialty polymers with tailored physical properties.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	1-(((tert-Butoxycarbonyl)Amino)Methyl)Spiro[2.5]Octane-1-Carboxylic Acid
CAS No.	724773-53-9
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	1-(((Boc-Amino)Methyl)Spiro[2.5]Octane-1-Carboxylic Acid; 1-((((tert-Butoxycarbonyl)Amino)Methyl)Spiro[2.5]Octane-1-Carboxylic Acid; 1-((Boc-Aminomethyl)spiro[2.5]octane-1-carboxylic acid; 1-((((tert-Butoxycarbonyl)Amino)Methyl)Spiro[2.5]Octane-1-Carboxylic Acid; 1-(((tert-Butoxycarbonyl)Amino)Methyl)Spiro[2.5]Octane-1-Carboxylic Acid; Boc-AM-Spiro[2.5]Octane-COOH; (1-((((tert-Butoxycarbonyl)Amino)Methyl)Spiro[2.5]Octan-1-yl)Methanoic Acid
EINECS	Contact for details

Quality Control

Our production of 1-(((tert-Butoxycarbonyl)Amino)Methyl)Spiro[2.5]Octane-1-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and cGMP manufacturing. Each lot is fully characterized by NMR, HPLC, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, and we support regulatory documentation requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.