Description

1-Aminomethyl-Spiro[2,5]Octane-1-Carboxylic Acid is a specialized spirocyclic amino acid derivative, serving as a high-value building block in advanced organic synthesis. Its unique constrained spiro[2,5]octane scaffold is prized for introducing three-dimensional complexity and influencing the conformational properties of target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Peptidomimetics: Used to construct conformationally restricted peptide analogs to enhance metabolic stability and receptor selectivity.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Potential monomer for synthesizing specialty polymers with unique thermal and mechanical properties.

Basic Information

Product Name	1-Aminomethyl-Spiro[2,5]Octane-1-Carboxylic Acid
CAS No.	724772-97-8
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	1-(Aminomethyl)spiro[2.5]octane-1-carboxylic acid; 1-Aminomethyl-1-carboxyspiro[2.5]octane; Spiro[2.5]octane-1-carboxylic acid, 1-(aminomethyl)-; 1-Carboxy-1-aminomethylspiro[2.5]octane; (1-Aminomethyl)spiro[2.5]octane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Aminomethyl-Spiro[2,5]Octane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and NMR for structural confirmation, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.