Description

2-[4-[(Fmoc-Amino)Methyl]Phenoxy]Acetic Acid is a specialized, high-purity building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, reliable intermediates for constructing complex molecules. It is primarily utilized in the pharmaceutical and biotechnology sectors for solid-phase peptide synthesis (SPPS) and the development of novel drug candidates and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected linker or handle for the controlled assembly of peptides on resin.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Acts as a versatile spacer arm for attaching peptides, labels, or other functional groups to surfaces, polymers, or biomolecules.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery.
• Proteomics Research: Utilized in the synthesis of modified peptides and affinity probes for studying protein function and interactions.
• Material Science: Can be incorporated into functionalized materials and hydrogels for biomedical applications.

Basic Information

Product Name	2-[4-[(Fmoc-Amino)Methyl]Phenoxy]Acetic Acid
CAS No.	721939-61-3
Molecular Formula	C24H21NO5
Molecular Weight	403.43 g/mol
Synonyms	Fmoc-PAL-OH; N-α-Fmoc-4-aminomethylphenoxyacetic acid; 4-[(9-Fluorenylmethoxycarbonylamino)methyl]phenoxyacetic Acid; Fmoc-4-Aminomethylphenoxyacetic Acid; PAL Linker for Fmoc SPPS; Fmoc-AMPA; (9H-Fluoren-9-yl)methyl N-[(4-hydroxyphenyl)methyl]carbamate acetate; 2-{4-[(Fmoc-amino)methyl]phenoxy}acetic acid
EINECS	Contact for details

Quality Control

Our 2-[4-[(Fmoc-Amino)Methyl]Phenoxy]Acetic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and production. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.